Chalcone Derivatives as Multitarget Modulators of Signalling Pathways in Breast Cancer: Mechanisms, Challenges, and Future Perspectives.
Breast cancer continues to be one of the leading causes of morbidity and mortality for women all over the world, noted for its heterogeneity, metastasis, and resistance to conventional therapies. In this regard, chalcone derivatives, which are flavonoids found in nature or synthesized chemically, are emerging as promis...