Richard H. Fish

Bioactivity studies of organometallic Cp*Rh(iii) and Au(i) NHC complexes bioconjugated to integrin binding peptides

Integrins are pivotal targets in cancer therapy development due to their overexpression in many tumor cells and neovascular tissue. Arginine–glycine–aspartic acid (RGD) sequence-containing peptides are established ligands for targeting integrins; approximately half of all known integrins recognize this sequence, enabli...