Author

Richard K. Lacher

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Open access Sep 2026

Atlas-based electrical source imaging for mouse EEG: Application to an Fmr1 knockout model

An atlas-based ESI pipeline for 30-channel mouse EEG is built and tested against simulated dipoles, but cannot show that a labeled region is the true source in a live animal, and replication across recording systems, sex, age and injection-naive animals is needed.

Alex D. Edmondson, Andrew D. Gaulden, Richard K. Lacher et al. · NeuroImage · 0 citations

Open access Jul 2026

FMR1 gene therapy restores translationally relevant phenotypes in a mouse model for fragile X syndrome.

It is shown that FMR1 gene therapy using delivery routes and vehicles approved for clinical use improves core phenotypes in a mouse model for FXS, and suggests that a dual route may be needed to achieve full brain coverage.

Richard K Lacher, Kari Henson, Lindsay N Wathen et al. · Gene Therapy · 0 citations