Open access
Oct 2026
Arc represses gene expression in IS605-family transposons
It is shown that Arc acts as a transcriptional repressor to directly bind the transposon’s native promoter sequence regulating TnpA and TnpB gene expression, revealing a regulatory layer that may promote long-term persistence of IS605-family elements by keeping their activity in check.
Younggi D. Moon, Rimantė Žedaveinytė, T. Wiegand et al.
· bioRxiv · 0 citations