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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Rita Turcio

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2 papers indexed here

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Open access Aug 2026

Molecular Basis for Activation to Inhibition Switching in Kv7.2 Channel Modulators

Novel mechanistic insights are provided into the molecular mechanisms governing Kv7 channel modulation by exogenous ligands which may prove useful to target Kv7 channels with more potent and selective modulators.

T. Ciaglia, G. Carleo, Zhenni Yang et al. · 0 citations
Open access Jul 2026

Development of Potent G Protein Pathway-Biased GPR183 Agonists

The detailed structure-activity investigations and optimizations led to the identification of full agonists for GPR183 with complete bias for Gαi protein signaling and low nanomolar potency, including 63 (TUG-2604) with potency and efficacy similar to 7α,25-OHC.

Kaustubh R. Bhuskute, Asmita Manandhar, V. M. S. Kjær et al. · 0 citations

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