Author

Robert A. Keyzers

2 papers indexed here

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Review Open access Sep 2026

Yeast chemical genetics to investigate mechanism of action of Pacific natural products.

Natural products are a major source of bioactive molecules with important applications in medicine, and investigation of species native to the Pacific region has been particularly fruitful, including species used in traditional and Indigenous medicinal practices. Yeast represents a powerful model system for investigati...

Robyn J. Ooi, Hannah F. Robinson, Ruth Pay et al. · FEMS Yeast Research · 0 citations

Open access Sep 2026

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont.

Peloruside A, a polyketide macrolide identified in the marine sponge Mycale hentscheli, is a promising anticancer drug candidate due to its ability to stabilize tubulin at a nontaxoid binding site. Substantial efforts were made to improve the supply of this scarce substance through chemical synthesis and mariculture, h...

A. Fraley, M. Rust, Moritz Wagner et al. · Angewandte Chemie · 0 citations