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Robert C. Barber

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Sep 2026

APOE:RAAS epistasis as a population specific risk factor for cognitive impairment and cardiovascular health.

BackgroundThe strongest genetic risk factor for development of Alzheimer's disease (AD) and/or AD-related dementias is the ε4 allele in the apolipoprotein E (APOE) gene, though the frequency and impact of this variant on cognitive decline can vary across populations. Vascular and metabolic disorders (e.g., hypertension...

Amanda E. Tucker, Robert C. Barber, Zheng-Yang Zhou et al. · 0 citations

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