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Author

Robert C. Jones

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Open access Aug 2026

Hypothalamic Cell Type Evolution across Vertebrates

The hypothalamus regulates vital functions and is highly conserved among vertebrates occupying diverse niches, but little is known about the evolution of its cell types. Using comparative single-cell transcriptomics across major vertebrate classes, we identified deeply conserved and clade-specific cell types. While hom...

Yun-Ming Wu, Prateek Kalakuntla, Billie C. Goolsby et al. · 0 citations
Open access Sep 2026

Single-cell splice isoform usage reveals distinct axes of cellular identity and senescence

A cross-tissue single-cell long-read isoform atlas spanning 26 human tissues is presented and it is demonstrated that isoform usage is a structured, measurable axis of cellular identity that is distinct from gene expression.

Madhav Mantri, A. Detweiler, Jaeyoon Lee et al. · 0 citations

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