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Robert C. Orchard

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Open access Sep 2026

Plscr1 inhibits murine norovirus entry

Noroviruses are a leading cause of gastroenteritis worldwide, yet host factors that restrict norovirus replication are not well understood. By mining both CRISPR activation and CRISPR knockout genome-wide screens, we identified the interferon-stimulated gene Plscr1 as a restriction factor for murine norovirus (MNV). Pl...

Nina S. Baggett, Linley R. Pierce, Robert C. Orchard · 0 citations

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