BACKGROUND
Proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab reduced the risk of a first major adverse cardiovascular event (MACE) in patients at high cardiovascular risk with no prior myocardial infarction (MI) or stroke in the VESALIUS-CV (Effect of Evolocumab in Patients at High Cardiovascular...
José C. Nicolau, Sabina A. Murphy, Robert P. Giugliano et al.· Journal of the American Coll...· 1 citation
BACKGROUND
Evolocumab, a PCSK9 (proprotein convertase subtilisin-kexin type 9) inhibitor, significantly reduced the risk of cardiovascular events in patients without previous myocardial infarction or stroke in the VESALIUS-CV trial (Effect of Evolocumab in Patients at High Cardiovascular Risk without Prior Myocardial I...
Robert P. Giugliano, E. Bohula, A. Bellavia et al.· Circulation· 0 citations
Olezarsen reduced triglycerides across the hypertriglyceridemia spectrum, with greater effects in patients on background fibrates, particularly with diabetes, to support potential complementary mechanisms and further investigation of concomitant triglyceride-reducing therapy.
Annabel Z. Wang, V. Alexander, T. Prohaska et al.· Journal of Clinical Lipidolo...· 1 citation
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