Open access
Sep 2026
Accelerated discovery of thermostable vaccines using data-efficient AI
The inherent instability of mRNA-lipid nanoparticles (LNPs) necessitates ultra-cold storage, creating significant barriers for global distribution and limiting their broader application in advanced delivery systems. Solid-state, water-free formulations offer a promising solution by enhancing thermostability and enablin...
Jin-Bi Tian, Khanh T. M. Tran, Brett H. Pogostin et al.
· bioRxiv · 0 citations