Molecular Engineering of Aptamers for Glioblastoma Therapy: From Simple Antagonists to AI-Driven Approaches, a Narrative Review
Computational strategies ranging from machine learning-guided sequence optimization to structure prediction and generative AI have accelerated the rational design of aptamers tailored to GBM specific challenges, enabling the development of innovative aptamer drug conjugates for targeted delivery to GBM cells.
L. Di Leandro, Martina Colasante, M. Catanesi et al.
· International Journal of Mol... · 0 citations