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R. Phadke

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Review Open access Sep 2026

Neuroimmune Phenotyping as the Next Frontier in Chronic Pain Medicine for Musculoskeletal Back Pain

Chronic low back pain encompasses heterogeneous mechanical, neuropathic, nociplastic, and myofascial presentations that may reflect distinct neuroimmune mechanisms. We synthesized evidence linking these phenotypes to measurable biological features and clinically relevant treatment strategies. We conducted a structured...

Samer G. Salman, Rohan A. Phadke, Adithya Nair et al. · 0 citations
Open access Aug 2026

Impact of Immunosuppression Type on 30-Day Postoperative Outcomes Following Anterior Cervical Discectomy and Fusion: A Retrospective National Cohort Study of 66,162 Patients

Study Design Retrospective Cohort Study. Objectives Perioperative immunosuppression management in spine surgery lacks robust evidence. Most NSQIP-based ACDF models utilize a binary steroid variable, failing to distinguish corticosteroids from biologics or synthetic DMARDs. This study uses the granular NSQIP immunosuppr...

R. Phadke, Samer G. Salman, Connor Welsh et al. · 1 citation
Review Open access Aug 2026

Large Language Models in Spine Surgery: A Scoping Review of Clinical Efficacy, Technical Integration, and Ethical Paradigms

Current evidence does not support autonomous diagnostic, radiographic, or operative decision-making in spine surgery, and future studies should prioritize spine-specific retrieval-augmented systems, validated multimodal workflows, privacy-preserving deployment, fairness assessment, and prospective evaluation using clin...

Samer G. Salman, R. Phadke, Anne E Tatooles et al. · 2 citations

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