Author

Rohit Bhatia

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Review Oct 2026

Thiazole-based Anticancer Agents: Synthetic Strategies, Molecular Mechanisms, Comparative Structure-activity Relationships, and Rational Design Perspectives.

Cancer continues to represent a major global health challenge, prompting the search for new therapeutic agents with improved efficacy and reduced toxicity. Among heterocyclic scaffolds, thiazole has attracted considerable attention in medicinal chemistry because of its structural versatility, synthetic accessibility, a...

Lovish Sharma, Ankur Thakur, Rohit Bhatia et al. · Mini-Reviews in Medical Chem... · 0 citations

Review Sep 2026

Artificial Intelligence-Driven Strategies for Predicting, Personalizing, and Optimizing Therapeutic Targets in Inflammatory Bowel Disease.

Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, represent chronic relapsing inflammatory disorders characterized by complex interactions among genetic, microbiome-related, immunological, and environmental factors. Although advances in biologics and small-molecule inhibitors have exp...

Priyanka Paul, Ankush Kumar, Rajwinder Kaur et al. · Current Medicinal Chemistry · 0 citations

Review Open access Aug 2026

Pyridopyrimidines and Pyridopyrimidinones as Kinase-Targeted Anticancer Agents: Medicinal Chemistry and Mechanistic Insights

Overall, pyridopyrimidine- and pyridopyrimidinones-based compounds continue to show great promise as potential anticancer agents and further research combining synthetic chemistry, biological studies, and computational approaches may lead to the development of more effective and safer drugs in the future.

Ankush Kumar, Rajwinder Kaur, Bhupinder Kumar et al. · Molecules · 0 citations