Open access
Jul 2026
High-level ciprofloxacin resistance in Pseudomonas aeruginosa is associated with genomic adaptation, collateral antibiotic susceptibility, and physiological trade-offs
High-level ciprofloxacin resistance in P. aeruginosa involves non-target-site genomic adaptations and physiological trade-offs beyond classical target mutations and reveals secondary adaptive trade-offs that can be targeted for clinical diagnostic and therapeutic decision-making.
Abhijeet Sahu, Rohit Ruhal
· bioRxiv · 0 citations