Author

Roiuk Mykola

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Open access Aug 2026

Stress induces DCP2 translation via a stalling-dependent mechanism

DCP2, encoding a major mRNA decapping enzyme, is identified as a previously unrecognized ISR-induced transcript and it is shown that translational induction of DCP2 depends on an overlapping ORF whose conserved 3′ region, corresponding to a ribosome pausing site, acts as a potent inhibitory element.

Roiuk Mykola, Marilena Neff, Taja Vatovec et al. · bioRxiv · 0 citations