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Romain Koszul

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Open access Oct 2026

Genome-wide chromatin reset at the onset of leg regeneration in pancrustaceans

Regeneration requires injured tissues to selectively reactivate certain developmental programs while triggering regeneration-specific mechanisms and responding to the immediate consequences of tissue damage. How chromatin states are reorganized during this transition, and whether the underlying sequence of regulatory e...

Maëlle Louvier, Gillian Forbes, Mahmood Mohammed-Ali et al. · 0 citations
Open access Dec 2025

Bacteriophage PAK_P3 genome structuration and dynamics during infection of Pseudomonas aeruginosa reveal specific interaction patterns

Bacteriophages, or phages, are highly abundant and diverse genomic entities that play an important role in microbial ecology, evolution, and horizontal gene transfer. While the dynamic changes in genome organization in cellular organisms have been well described, the 3D folding of phage genomes during the infection of...

Amaury Bignaud, Quentin Lamy-Besnier, Devon E. Conti et al. · 0 citations
Open access Aug 2026

Chromatin is dispensable for bacterial life

The successful construction of ΔNAP9 demonstrates that bacterial cells can carry out basic cellular functions in the absence of co-evolved chromatin proteins, highlighting the potential for radical (re-)engineering of prokaryotic chromatin and systems of gene expression.

Paul Villain, A. Hocher, Jacques Serizay et al. · 1 citation

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