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Author

Rong-Bin Hu

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Open access Sep 2026

Naturally Occurring 2-Methoxy-1,4-naphthoquinone Attenuates Biofilm Formation and Quorum Sensing-Regulated Virulence in Pseudomonas aeruginosa

Pseudomonas aeruginosa employs quorum sensing (QS) to coordinate biofilm formation and virulence factor expression, positioning QS as a promising target for anti-infective interventions. This study evaluated the antibiofilm and antivirulence efficacy of 2-methoxy-1,4-naphthoquinone (MNQ), a natural naphthoquinone, agai...

Rong-Jia Han, Yu-Ting Bai, Ya-Xin Zhou et al. · 0 citations
Open access Sep 2026

Mechanism of Synergistic Action of Isochlorogenic Acid C and Ciprofloxacin Against Drug-Resistant Escherichia coli

Background: The rapid emergence of antibiotic resistance in E. coli has outpaced the development of new drugs, creating an urgent demand for novel therapeutic strategies. Methods: We screened ten antibiotics in combination with isochlorogenic acid C (ICAC) against multidrug-resistant (MDR) E. coli. Synergistic effects...

Yu-Bin Bai, Xu Chen, Rong-Bin Hu et al. · 0 citations

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