Dihydroartemisinin overcomes cisplatin resistance in bladder cancer via suppression of the PI3K/AKT/ABCB1 signaling Axis
Cisplatin resistance substantially limits the efficacy of bladder cancer chemotherapy, and effective strategies to overcome resistance remain insufficient. In this study, we demonstrate that dihydroartemisinin (DHA) restores cisplatin sensitivity in resistant bladder cancer cells by suppressing the PI3K/AKT/ABCB1 sig...