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Open access Aug 2026

All-optical multimodal mapping of single-cell-type-specific metabolic activities via REDCAT

Metabolism is fundamental to cell function, yet its activities vary across tissue environments. Resolving these processes in situ at single-cell resolution is crucial for understanding physiology in health and disease. However, existing methods lack biochemical specificity or direct linkage to cell identity. Here we re...

Ya-Juan Li, Zhao-Jun Zhang, Archibald Enninful et al. · 0 citations
Open access Sep 2026

Spatial chromatin architecture and accessibility co-profiling of mammalian tissues.

Cellular function depends on the spatial organization of cells and biomolecules within the tissue microenvironment. Advances in spatial omics have enabled profiling of molecular features such as transcriptome, proteome and epigenome, and there has been rapid progress of imaging-based approaches to study spatial three-d...

Ping Wang, Juan Wang, Qi-Xuan Wang et al. · 0 citations

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