CircNFIB attenuates hypoxia/reoxygenation-induced ferroptosis in AC16 cardiomyocytes with involvement of the miR-338-3p/GPX4 pathway.
Cardiomyocyte ferroptosis contributes to myocardial ischemia/reperfusion injury, but the upstream noncoding RNA mechanisms remain incompletely defined. This study examined whether nuclear factor I B-derived circular RNA (circNFIB) regulates hypoxia/reoxygenation (H/R)-induced ferroptosis in human ventricular cardiomyoc...