The Platelet–Adipose Tissue Axis in Metabolic Disease: From Platelet Reprogramming to Tissue Remodeling
Obesity-induced adipose tissue remodeling results from the interplay of metabolic stress, chronic inflammation, extracellular matrix remodeling, and vascular dysfunction. Beyond their established role in thrombosis, platelets have emerged as immunometabolic effectors at the interface between vascular and metabolic resp...