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Author

Roxana-Andra Coman

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Review Open access Sep 2026

Gut Dysbiosis, Uremic Toxins, and NLRP3 Signaling in Chronic Kidney Disease: From Mechanistic Evidence to Clinical Biomarker Evaluation

The gut–toxin–inflammasome axis is mechanistically plausible, but evidence for priming is substantially stronger than that for direct activation and evidence for priming is substantially stronger than that for direct activation.

Imola Donath-Miklos, O. Știrbu, R. Popețiu et al. · 0 citations
Review Open access Aug 2026

Circulating Tumor Function: A Systems Biology Framework for Liquid Biopsy in Genitourinary Cancers

Liquid biopsy enables minimally invasive detection and longitudinal monitoring of tumor-derived material in blood and urine. In genitourinary cancers, most applications have focused on genomic alterations in circulating tumor DNA (ctDNA), together with circulating tumor cells (CTCs), extracellular vesicles (EVs), and c...

Roxana-Andra Coman, A. Nutu, Lia-Raluca Olari et al. · 0 citations

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