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Author

Roy Freeman

1 paper indexed here

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Open access Aug 2026

Cutaneous Alpha-Synuclein Deposition Informs Autonomic Function in Individuals with Early-Stage Multiple System Atrophy

Cutaneous phosphorylated alpha-synuclein deposition increased over time and correlated with objective orthostatic hypotension and autonomic symptom burden in early synucleinopathy, and may serve as a minimally invasive tool to support diagnosis, monitor progression, and stratify clinical trial participants.

P. Trujillo, Leah G. Mann, B. Bellaire et al. · 1 citation

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