Background: Arthritis is a major cause of pain, functional limitation, and disability among middle-aged and older adults. Although allostatic load (AL) and depressive symptoms have each been linked to adverse health outcomes, prospective evidence on their independent and joint associations with incident arthritis remai...
Ru Feng, Min Ni, Xiao-Xin Wang et al.· Healthcare· 0 citations
Macrophages and microglia serve as both "scavengers" and "immune sentinels" to maintain tissue homeostasis. However, when the lipid load exceeds their processing capacity, these cells transform into foam cells, thereby driving chronic inflammation and impairing tissue repair. Despite their distinct organ systems, ather...
Gui-Na Tan, Xiao-Xin Wang, Jing Chen et al.· Journal of Lipid Research· 0 citations
The classification systems, preparation methods, and the molecular mechanisms and application progress of PRP in neural repair are reviewed to provide a theoretical basis and practical reference for further research and clinical translation of PRP in the field of neural repair.
Gui-Na Tan, Xiao-Xin Wang, Jing Chen et al.· Frontiers in Immunology· 0 citations
This review explores the sophisticated multi‐level regulation of UCHL1, ranging from transcriptional control to epigenetic silencing and posttranslational modifications, summarizes the recent research progress of UCHL1 in various systems, and elaborates on its mechanism of action.
Ru Feng, Xiu Zhong, Jian-Jun Li et al.· Immunology and Cell Biology· 0 citations
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