Review
Open access
Oct 2026
Anticoagulants beyond coagulation: repurposing heparin to mitigate immunothrombosis and inflammatory cascades in sepsis
Sepsis is a life-threatening syndrome caused by a dysregulated host response to infection, in which inflammation, coagulation, endothelial injury, and immune dysfunction interact to drive organ failure and death. Accumulating evidence identifies immunothrombosis as a central mechanism in this process, linking neutrophi...
Yan-Ming Ren, Hong-Qiong Meng, Bei-Bei Li et al.
· Frontiers in Pharmacology · 0 citations