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Review Open access Aug 2026

Synthetic microbial communities: emerging live biotherapeutics for targeted gut microbiome modulation

This review established strict boundaries between SynComs and traditional donor-derived preparations, comparatively evaluating “top-down” and “bottom-up” construction strategies, and explored the mechanisms underlying the SynComs-mediated synergistic restoration of intestinal homeostasis via direct targeted antagonism...

Ru Zhang, Hong-Ye Li, Chun-Feng Wang et al. · 0 citations

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