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Rüdiger Köhling

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Open access Sep 2026

Comparison of amyloid-β, total tau and phospho-tau in clinical AD patients with and without epileptiform EEG patterns.

BACKGROUND Epilepsy is a relevant comorbidity of dementia due to Alzheimer's Disease (AD) and probably directly related to its pathology. We aimed to generate hypotheses how interictal epileptiform discharges (IEDs) may be associated with pathological levels of AD markers from cerebrospinal fluid (CSF). OBJECTIVE To...

Livia Rabea Ott, W. Hermann, Rüdiger Köhling et al. · 0 citations
Open access Aug 2026

XE991 Reverses Enhanced Short-Term Plasticity in Rat Epileptic CA1

Background/Objectives: Recent evidence has suggested a transcriptional reduction in Kv7 potassium channels in the CA1 area of acquired experimental epilepsy, but presynaptic Kv7 channels might be spared. Here, we tested the influence of the Kv7 channel blocker XE991 on two forms of short-term plasticity, which are supp...

Emma Schnell, Steffen Müller, Rüdiger Köhling et al. · 0 citations

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