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Ruhban Ansar Parry

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Sep 2026

Abstract B065: Bioactive Compounds Derived from Alcea rosea Suppress KRAS-Driven Signaling and Cancer Stem Cell Plasticity in Pancreatic Ductal Adenocarcinoma

Activating KRAS mutations occur in more than 90% of pancreatic ductal adenocarcinoma (PDAC) cases and are major drivers of tumor progression, therapeutic resistance, and poor clinical outcomes. Persistent activation of the RAF/MEK/ERK signaling cascade promotes cancer stem cell (CSC) maintenance and tumor plastic...

Ruhban Ansar Parry · 0 citations

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