Open access
Aug 2026
Predicting Protein-RNA Binding Affinity Changes via Spatial Coupling-Aware State Space Modeling
iSCALE serves as an effective in silico tool for large-scale protein-RNA binding ΔΔG prediction, which pushes the border of understanding in mutation-induced pathological outcomes.
Rui Chen, Xiaoyu Huang, Huasen Jiang et al.
· bioRxiv · 0 citations