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Review Open access Sep 2026

Methods to Address Compositional Data Challenges in Clinical Studies for the Safety Assessment of Human Microbiome Perturbations.

Advances in sequencing technologies have enabled increasingly detailed characterisation of the human microbiome in clinical studies, but interpretation of microbiome modulation which has relevance to health and disease characterisation or safety assessments remains methodologically challenging. Taxonomic profiles gener...

Aline Métris, Rui Guan, Antonis Ampatzoglou et al. · 0 citations
Open access Jan 2025

Obligate cross-feeding of metabolites is common in soil microbial communities

Many microorganisms are refractory to laboratory cultivation. One possible explanation, known as the great plate count anomaly, is metabolic dependencies among community members. However, systematic studies of these interactions in communities like soil are missing, hindering advances in understanding these ecologicall...

Ghada Yousif, Francisco Zorrilla, Swagatika Dash et al. · 9 citations · ⚡1

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