Author

Rui Huang

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Preprint Sep 2026

Reliability assessment and multicenter clinical application of magnetic resonance methods for knee cartilage quantification

Background: This study evaluated interreader agreement and longitudinal performance of MRI methods for knee cartilage volume, thickness, and defect-area quantification. Methods: AI-presegmented masks from 1,189 phase III examinations underwent independent correction by two readers and adjudication. Cartilage volume, th...

Bin-Bin Yang, Yong-Mei Jian, Cheng-Lei Liu et al. · 0 citations

Preprint Sep 2026

Development, Evaluation, and Multicenter Clinical-Trial Application of an Artificial Intelligence-Assisted MRI Method for Quantitative Knee Cartilage Morphometry

Objective: To develop and evaluate an AI-assisted MRI method for quantitative knee cartilage morphometry in a multicenter phase III knee osteoarthritis trial. Methods: AI pre-segmentation used 3D full-resolution nnU-Net. Version 1.0 used separate femorotibial- and patellar-cartilage models, whereas version 2.0 used a u...

Bin-Bin Yang, Rui Huang, Yuan-Jing Xu et al. · 0 citations