Peripheral CHOP+ CD4+ T-Cell Subsets Are Reduced and Clinically Relevant in Primary Sjögren's Syndrome.
OBJECTIVE Primary Sjögren's syndrome (pSS) is an autoimmune disease characterized by lymphocytic infiltration of exocrine glands and systemic immune dysregulation. Endoplasmic reticulum stress (ERS)-related transcription factor C/EBP homologous protein (CHOP) has been implicated in several autoimmune conditions, but it...