Open access
Sep 2026
L-Threonic Acid Inhibits Pathological Retinal Neovascularization by Modulation of CCL3–CCR5 Signaling Pathway
Cross-tissue metabolomics revealed L-ThA as a metabolite consistently downregulated in PDR; functional studies suggest it possesses anti-angiogenic effects by modulation of CCL3–CCR5 signaling, representing a potential biomarker and therapeutic target for PDR.
Hong-Yan Sun, Lan Zhou, Tian-Yi Luo et al.
· Investigative Ophthalmology... · 0 citations