Author

Rui Tao

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Sep 2026

Targeting LAMP2 synergizes with gemcitabine to inhibit bladder cancer progression via modulating STING degradation and regulating macrophage phenotypes

The intrinsic role of LAMP2 in BLCA progression is clarified and MRGPRX4 modulator-2 (Mm-2), a LAMP2-binding small molecule with anti-tumor activity against BLCA, is identified as a candidate LAMP2-targeting agent acting on STING signaling via drug screening and molecular docking.

Yue Lv, Qiang Yin, Wu Li et al. · Apoptosis · 0 citations

Open access Aug 2026

Burden of early-onset pancreatic cancer and its association with risk factors in women of childbearing age

The global EOPC burden among WCBA and its links to core metabolic determinants are delineated, providing an evidence base to guide targeted interventions in this priority population and support progress toward international development goals.

Jiaxing Li, Jing Luo, Qi-Hui Hu et al. · PLoS ONE · 0 citations