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Open access Sep 2026

Ablation of a maternal Cryptosporidium mRNA-binding protein results in sterile sporozoites

Infection with Cryptosporidium is a leading cause of diarrheal disease and early childhood mortality. This apicomplexan parasite undergoes asexual and sexual replication within the same host and recent studies have shown an intrinsic developmental program of obligate transition to male and female gametes and sex. While...

Abigail M. Daniels, Sebastian Shaw, Christopher Nötzel et al. · 0 citations
Open access Oct 2026

Diverse infections transcriptionally reprogram the intestinal epithelium and epithelial-immune cell interactions.

The distal small intestine has a vital role in host physiology through its regulation of nutrient and fluid homeostasis. Despite being affected in Crohn's disease and serving as a major target for a range of infections, we know relatively little about the complexity of cellular responses and cell-cell communication in...

A. Hart, Maria I. Merolle, Christian A. Howard et al. · 0 citations

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