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Rui-Xue Zhao

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Open access Jul 2026

EPAS1 knockdown is associated with cell cycle and DNA replication programs and MYC/E2F-related signatures in hemangioma endothelial cells

In IH tissue transcriptomic data, Egl-9 family hypoxia-inducible factor 3 (EGLN3) showed reduced expression, consistent with a testable hypothesis that hypoxia-independent mechanisms may contribute to maintenance of HIF-2α activity in this context.

Zheren Su, Lu-Ying Wang, Rui-Xue Zhao et al. · 0 citations
Open access Jul 2026

FOXM1-associated melanoma stratification: integrated multi-omics and experimental validation reveal prognostic significance and therapeutic potential

Functional analyses indicated that FOXM1 was primarily involved in cell-cycle progression and mitotic regulation, and its overexpression is associated with aggressive tumor behavior, and functional inhibition suppresses malignant phenotypes, highlighting its potential value for risk stratification and therapeutic targe...

Zhi-Chen Li, Zhen-Peng Zhu, Rui-Xue Zhao et al. · 0 citations

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