Case report
Open access
Sep 2026
Case Report: Possible spatially-distinct de novo invasive cervical carcinoma in the setting of isolated persistent HPV16 after ALA-PDT-mediated histological clearance of CIN3
Background Cervical intraepithelial neoplasia grade 3 (CIN3) is a high-grade precancer, and 5-aminolaevulinic acid-mediated photodynamic therapy (ALA-PDT) offers a fertility-preserving alternative for young patients. However, complete lesion regression does not eliminate the latent oncogenic risk of persistent HPV16, a...
Huihui Cai, Yan-Ci Che, Yu-Tong Liu et al.
· Frontiers in Medicine · 0 citations