Rui-Ze Tang

Case Report: Melanocyte-associated mTORC1-related molecular features in an atypical large congenital melanocytic naevus

Congenital melanocytic naevi (CMN) are usually associated with activating alterations in NRAS or BRAF , but some extensive lesions lack detectable canonical hotspot variants. We report a 9-year-old boy with a large craniofacial CMN involving the face, scalp, upper eyelid and bulbar conjunctiva, with deep extensio...