Glioblastoma is the most aggressive and fatal primary malignant brain tumour in adults, characterised by extensive intra-tumour heterogeneity, diffuse infiltration into surrounding brain tissue. Despite advances in surgery, radiotherapy, and chemotherapy, patient prognosis remains poor, underscoring the critical need f...
L. Prakash, Ruman Rahman· Current Oncology Reports· 0 citations
Glioblastoma (GBM) recurrence is driven by residual disease that infiltrates beyond the resection margin, a region poorly characterised at the molecular level. Fluorescence-guided surgery using 5-aminolevulinic acid (5ALA) identifies metabolically active invasive tumour populations and provides an opportunity to...
Maria Shah, Stuart Smith, E. Bakker et al.· Neuro-Oncology· 0 citations
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