Run-Bin Yan

Sufentanil attenuates LPS-induced acute lung injury by suppressing ferroptosis and maintaining GPX4 protein abundance

Introduction Acute lung injury (ALI) is a severe inflammatory syndrome characterized by disruption of the alveolar-capillary barrier, pulmonary edema, and impaired gas exchange. Ferroptosis has emerged as an important contributor to ALI pathogenesis, but the mechanisms associated with reduced glutathione peroxidase 4 (...