Run-Jia Zhang

T-cell–driven immune modulation in osteoarthritis: deciphering the hADSC–macrophage cross-talk

Osteoarthritis (OA) has traditionally been regarded as a mechanically driven degenerative joint disorder. However, recent advances in single-cell sequencing, spatial omics, and immunohistochemical analyses have revealed that OA is also characterized by persistent low-grade inflammation and complex immune dysregulatio...