Construction, expression, and immunogenicity analysis of a fusion gene based on the PE/PPE family in combination with adjuvants.
Tuberculosis (TB) remains the leading global cause of death from a single infectious agent and a major fatal infectious disease worldwide. However, the Bacillus Calmette-Guérin (BCG) vaccine-currently the only licensed TB vaccine in clinical practice-has critical limitations in preventing latent infection and disease r...