Margin-enriched CD4+ central-memory T cells affect macrophages via ANXA1-FPR1 signaling axis to promote tumor progression in intrahepatic cholangiocarcinoma
This study systematically characterized the features and distribution of CD4+ ANXA1+ Tcm cells in the margin zone of iCCA and investigated the potential mechanisms by which CD4+ ANXA1+ Tcm cells affected tumor progression, providing novel understanding of the function of these CD4+ Tcm cells in iCCA.