Ruo-Feng Sun

Anti-microbial diterpene alkaloids from the marine sponge Agelas nakamurai.

A chemical investigation of the CH2Cl2 extract of a sponge Agelas nakamurai guided by the molecular networking approach resulted in the isolation of 7 undescribed N-methylpurine diterpene alkaloids, namely nakamuranine A-G (1-7), in addition to (+)-8-epiagelasine T, agelasine D and (+)-agelamide D. Their structures wer...