Formononetin Protects Osteoblasts Against Oxidative Stress and Attenuates Ovariectomy-Induced Bone Loss in Association with MAPK/AP-1 and NRF2 Signaling
Postmenopausal osteoporosis (PMOP) is associated with estrogen deficiency and oxidative stress (OS), which impair osteoblast survival and osteogenic function. Formononetin (FMN) is a phytoestrogen with antioxidant properties, but its protective effects on osteoblasts under OS and the signaling pathways associated with...