The inflammatory response is a physiological defense mechanism that combats pathogens and removes damaged tissue to maintain homeostasis. However, excessive inflammation can lead to chronic diseases such as cardiovascular disorders, diabetes, and autoimmune conditions. Macrophages, key immune cells, play a central...
Cheng Zhang, Xin-Yi Liu, Wen-Lin Chen et al.· Phytochemicals in Food and M...· 0 citations
Macrophage foam-cell formation, triggered by excessive uptake of oxidized low-density lipoprotein (ox-LDL) and subsequent intracellular lipid accumulation, represents a critical pathological event in atherosclerotic plaque initiation that drives localized inflammatory responses. The present study investigated the effec...
To investigate the anticancer effects of Beauvericin (BEA) and elucidate its potential mechanisms in pancreatic cancer cells, a malignancy characterized by marked heterogeneity and frequent chemoresistance. The effects of BEA on the proliferation, migration and apoptosis of Mia PaCa-2 cells were evaluated via CCK-8,...
Xin-Yi Yu, Xiao-Dan Liu, Jie Ouyang et al.· Scientific Reports· 0 citations
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