Author

Ruochi Zhang

2 papers indexed here

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Open access Sep 2026

Similarity‐Enhanced Representation Learning of Non‐Canonical Amino Acids for Therapeutic Peptide Modeling

ABSTRACT Peptides combine the favorable pharmacokinetics of small molecules with the high specificity of biologics, making them promising therapeutics. Incorporating non‐canonical amino acids (ncAAs) further enhances drug‐like properties, yet modeling remains challenging due to chemically modified residues and combinat...

Chen-Cheng Xu, Le-Song Wei, Jian-Min Wang et al. · Advancement of science · 1 citation

#artificial intelligence Preprint Sep 2026

FLaG: Frequency-Domain Latent-attention Gated Pooling for Token Aggregation

Frequency-Domain Latent-attention Gated Pooling (FLaG), a plug-in aggregation module that re-expresses encoder outputs in the Fourier domain before final pooling, provides a transferable frequency-domain aggregation bias across protein, visual, and textual representations, with benefits that depend on the backbone and...

Ke-Wei Li, Rong Zhang, Xuelin Wang et al. · 0 citations