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Ruxandra D. Rotarescu

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Open access Sep 2026

Hepatic ELOVL2 regulates sex differences in mouse heart omega-3 polyunsaturated fatty acid metabolism.

Premenopausal females have higher docosahexaenoic acid (DHA, 22:6n-3) levels than males, with elongation of very long chain fatty acids-like 2 (Elovl2) implicated in regulating these differences. We employed a liver-specific Elovl2-KO model to determine how hepatic ELOVL2 activity influences sex differences in DHA synt...

Kuorosh Rezaei, Elaine Huang, Cherie Shum et al. · 0 citations

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