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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

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Ryuta Tabata

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Open access Aug 2026

Dose Optimization Design for Randomized Phase II Trials With Toxicity and Efficacy Endpoints

Several study designs for identifying optimal biological dose (OBD) have been proposed for phase I, II, and I/II clinical trials, considering toxicity and efficacy of anticancer drugs, especially molecular‐targeted therapies and immune checkpoint inhibitors. Among these, the multiple‐dose randomized phase II trial (MER...

Ryuta Tabata, Tomohiro Ohigashi, Takashi Sozu · 1 citation

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